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The main mechanism of ferroptosis Inhibiting the cysteine-glutamate transporter system Xc can induce ferroptosis System Xc is a sodium independent antiporter that export intracellular glutamate and import extracellular cystine across the membrane in a ratio of 1:1 to synthesize glutathione in cells [19]

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Glutathione is a tripeptide a small protein made from three amino acids: glutamine, cysteine, and glycine

10.19803/j.1672-8629.20230120 26 GarridoE.Botella de MagliaJ.CastilloO

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